PSSM2 stands for ”Polysaccharide Storage Myopathy Type 2“ and is an umbrella term for multiple muscle diseases with similar symptoms. … If a genetic test for PSSM1 was negative, but a biopsy showed disrupted muscle formation, the horse was diagnosed with PSSM2.
What are the symptoms of PSSM in horses?
Clinical signs of PSSM range from mild to severe. They include sweating, lameness, sore muscles, undiagnosed lameness, poor performance, and muscle tremors (“tying up”). These may occur with or without exercise. Under saddle, affected horses may be reluctant to go forward or collect.
What is pssm2?
Warmbloods with type 2 PSSM have painful firm back and hindquarter muscles, reluctance to collect and engage the hindquarters, poor rounding over fences, gait abnormalities, and slow onset of atrophy especially when out of work.
Is pssm2 hereditary?
Warmblood MFM has been shown to be genetic. A three-generation pedigree shows horses affected by Warmblood MFM, as scored by muscle biopsy, including electron microscopy . The pedigree suggests that Warmblood MFM is inherited as a dominant or semidominant trait.
How serious is PSSM in horses?
This is a serious situation, as it can damage the horse’s kidneys if they become dehydrated. Very young foals with PSSM occasionally show signs of severe muscle pain and weakness. This occurs more often if they have a simultaneous infection such as pneumonia or diarrhea.
What do you feed a horse with PSSM?
These low-starch feeds should be fed with good-quality grass hay or a maximum of 50 percent alfalfa hay. Regular turnout for as much time as possible is critical to successful management of PSSM horses. They do not do well confined to stalls or missing days of exercise.
Is PSSM in horses progressive?
The clinical characteristics of PSSM vary between breeds, from muscle pain, cramping and cell damage with exercise, to progressive muscle atrophy. … This mutation results in the accumulation of abnormal complex sugars within skeletal muscle of horses. This form of PSSM is termed Type 1 PSSM.
How do you test for PSSM?
Muscle Biopsy: PSSM can be diagnosed based on microscopic evaluation of a muscle biopsy in horses over two years-of-age, however, a definitive diagnosis of the type 1 form of PSSM requires genetic testing. The sample is taken from the semimembranosus muscle, which is part of the rear limb hamstring muscles.
What does N N mean in horses?
Selective breeding to normal (N/N) horses could entirely eliminate HYPP disease. As HYPP is inherited as a dominant condition, it can and is being spread to other breeds.
How common is PSSM in horses?
PSSM is most prevalent in American Quarter Horses and their related breeds (Paint horse, Appaloosa, Appendix Quarter Horse), Draft horse breeds (especially Belgian Draft and Percherons), and Warmblood breeds. The Belgian Draft been shown to have a 36% prevalence of PSSM.
What Quarter Horse bloodlines carry PSSM?
PSSM is a muscle disease in horses with Quarter Horse bloodlines such as Quarter Horses, American Paint Horses and Appaloosas.
What is RER horse?
Recurrent exertional rhabdomyolysis (RER) is an intermittent form of tying-up in horses that appears to involve an abnormality in intracellular calcium regulation as the possible cause.
How do you treat horse tying up?
If your horse ties up, here are suggestions of what to do:
- Stop exercising the horse and move it to a box stall. …
- Call your veterinarian.
- Blanket the horse if the weather is cool.
- Determine if the horse is dehydrated due to excessive sweating.
How much is a 5 panel test for horses?
Test kits for the five panel test can be obtained by request from the AQHA. For members, the test will cost $85. Nonmembers will pay $125. A five panel test in conjunction with the regular DNA test required for breeding stock will be $105 for members, $145 for nonmembers.
What causes muscle atrophy in horses?
Muscle wasting is a common feature of systemic infections and most malignant diseases. Muscle wasting is sometimes identified by a prominent spine along the back or neck. The loss of muscle mass in a horse can have other causes such as loss of fat, age related sarcopenia, and Cushing’s disease.